Intermittent systemic hypoxia – A possible way to improved regeneration
نویسندگان
چکیده
منابع مشابه
Invited review: Physiological consequences of intermittent hypoxia: systemic blood pressure.
One of the major manifestations of obstructive sleep apnea is profound and repeated hypoxia during sleep. Acute hypoxia leads to stimulation of the peripheral chemoreceptors, which in turn increases sympathetic outflow, acutely increasing blood pressure. The chronic effect of these repeated episodic or intermittent periods of hypoxia in humans is difficult to study because chronic cardiovascula...
متن کاملIntermittent hypoxia: cell to system.
This symposium was organized to present research dealing with the effects of intermittent hypoxia on cardiorespiratory systems and cellular mechanisms. The pattern of neural impulse activity has been shown to be critical in the induction of genes in neuronal cells and involves distinct signaling pathways. Mechanisms associated with different patterns of intermittent hypoxia might share similar ...
متن کاملPhysiological and Genomic Consequences of Intermittent Hypoxia Invited Review: Physiological consequences of intermittent hypoxia: systemic blood pressure
Fletcher, Eugene C. Invited Review: Physiological consequences of intermittent hypoxia: systemic blood pressure. J Appl Physiol 90: 1600–1605, 2001.—One of the major manifestations of obstructive sleep apnea is profound and repeated hypoxia during sleep. Acute hypoxia leads to stimulation of the peripheral chemoreceptors, which in turn increases sympathetic outflow, acutely increasing blood pre...
متن کاملPhysiological and Genomic Consequences of Intermittent Hypoxia Selected Contribution: Improved anoxic tolerance in rat diaphragm following intermittent hypoxia
THOMAS L. CLANTON1, VALERIE P. WRIGHT1, PETER J. REISER2, PAUL F. KLAWITTER3, AND NANDURI R. PRABHAKAR4 1Department of Internal Medicine, Pulmonary and Critical Care Medicine, The Dorothy Davis Heart and Lung Research Institute, 2Department of Oral Biology, College of Dentistry, and the 3Department of Emergency Medicine, The Ohio State University, Columbus, Ohio 43210; and 4Department of Physio...
متن کاملChronic intermittent hypoxia increases sympathetic responsiveness to hypoxia and hypercapnia.
We sought to determine whether chronic exposure to intermittent hypoxia (CIH) increases sympathetic responsiveness to subsequent chemoreflex stimulation. Sprague-Dawley rats were exposed to 30 days of CIH: exposure chamber %O2 [fractional concentration of chamber O2 (FcO2)] nadir 6.5-7% with return to 21% each minute for 8 h/day during the diurnal sleep period (Exp group). Sham controls (SC gro...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2019
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.2019.33.1_supplement.611.1